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  • It Was a Promising Addiction Treatment. Many Patients Never . . .
    Opioid addiction was far from rare, but O’Keeffe claimed buprenorphine would attract few patients, because it was still technically illegal for doctors to prescribe it for addiction treatment
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    In hope of providing more treatment options for opioid use disorder, the VCU research team reworked nor-levo-alpha-acetylmethadol, a metabolite of a previous FDA-approved opiate dependence medication, into a new formulation that could be used to help patients with opioid addiction
  • NIH research clears way for study of experimental treatment . . .
    The National Institutes of Health (NIH) today announced that its Investigational New Drug (IND) application for mitragynine, the primary psychoactive compound found in Mitragyna speciosa (kratom), has taken effect with the U S Food and Drug Administration (FDA) The IND paves the way for an NIH-led phase I clinical trial to evaluate mitragynine as a potential treatment for opioid use disorder
  • Opioid use disorder: current trends and potential treatments
    Abstract Opioid use disorder (OUD) is a major public health threat, contributing to morbidity and mortality from addiction, overdose, and related medical conditions Despite our increasing knowledge about the pathophysiology and existing medical treatments of OUD, it has remained a relapsing and remitting disorder for decades, with rising deaths from overdoses, rather than declining The COVID
  • Patient Information for SUBLOCADE® (buprenorphine extended . . .
    Learn about once-monthly SUBLOCADE, a treatment option for opioid addiction Get information on savings, resources, and how to get started See Safety Info, PI, Boxed Warning Med Guide
  • Medications for Substance Use Disorders | SAMHSA
    Medications for Substance Use Disorders Medications for Alcohol Use Disorder (MAUD) Medications for Opioid Use Disorder (MOUD) What is Buprenorphine? Buprenorphine is the first medication to treat opioid use disorder (OUD) that can be prescribed or dispensed in physician offices, significantly increasing access to treatment
  • AI model designs new treatment for opioid addiction
    Currently, the standard drugs used to address opioid use disorder are themselves opioids, which adds to the stigma around addiction and makes accessing treatment challenging
  • Medical Breakthrough Offers Hope To Those Fighting Addiction
    A new drug that helps people with a substance dependency detoxification —in five days—from opioids and alcohol without painful withdrawal symptoms recently completed a proof-of-concept
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    A new study published in JAMA Network Open on May 7, 2026, engaged 42 national experts in hospital-based addiction treatment in a consensus-building process to develop best practices for hospital





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