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graded    音标拼音: [gr'edəd] [gr'edɪd]
v. 定等级,定次序,评分
vbl. 定等级,定次序,

定等级,定次序,评分 定等级,定次序,

graded
adj 1: arranged in a sequence of grades or ranks; "stratified
areas of the distribution" [synonym: {graded}, {ranked},
{stratified}]

Grade \Grade\, v. t. [imp. & p. p. {Graded}; p. pr. & vb. n.
{Grading}.]
1. To arrange in order, steps, or degrees, according to size,
quality, rank, etc.
[1913 Webster]

2. To reduce to a level, or to an evenly progressive ascent,
as the line of a canal or road.
[1913 Webster]

3. (Stock Breeding) To cross with some better breed; to
improve the blood of.
[1913 Webster]


graded \graded\ adj.
1. ordered by some quantitative ranking; as, Reading tests of
graded difficulty.

Syn: ordered, ranked.
[WordNet 1.5]

2. leveled and drained but not paved; -- of roads.

Syn: graveled.
[WordNet 1.5]


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  • Estradiol - Wikipedia
    The name estradiol derives from estra-, Gk οἶστρος (oistros, literally meaning "verve or inspiration"), [107] which refers to the estrane steroid ring system, and -diol, a chemical term and suffix indicating that the compound is a type of alcohol bearing two hydroxyl groups
  • Aromatase - Wikipedia
    Aromatase is localized in the endoplasmic reticulum where it is regulated by tissue-specific promoters that are in turn controlled by hormones, cytokines, and other factors It catalyzes the last steps of estrogen biosynthesis from androgens (specifically, it transforms androstenedione to estrone and testosterone to estradiol) These steps include three successive hydroxylations of the 19-methyl group of androgens, followed by simultaneous elimination of the methyl group as formate and
  • Ethinylestradiol - Wikipedia
    Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins [7][8] Ethinylestradiol is widely used for various indications such as the treatment of menopausal symptoms, gynecological disorders, and certain hormone-sensitive cancers It is usually taken by mouth but is also used as a patch and vaginal ring [7][12] The general side effects of ethinylestradiol include breast tenderness and enlargement, headache, fluid retention
  • Pharmacokinetics of estradiol - Wikipedia
    The pharmacology of estradiol, an estrogen medication and naturally occurring steroid hormone, concerns its pharmacodynamics, pharmacokinetics, and various routes of administration [10][11][12] Estradiol is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol [10] Due to its estrogenic activity, estradiol has antigonadotropic effects and can inhibit fertility and suppress sex hormone production
  • Estradiol enanthate - Wikipedia
    Estradiol enanthate (EEn or E2-EN), also spelled estradiol enantate and sold under the brand names Perlutal and Topasel among others, is an estrogen medication which is used in hormonal birth control for women [1][2][11] It is formulated in combination with dihydroxyprogesterone acetophenide (DHPA; algestone acetophenide), a progestin, and is
  • Estrogen - Wikipedia
    Estrogen (US English [a]) or oestrogen (Commonwealth English) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics [1][2] There are three major endogenous estrogens that have estrogenic hormonal activity: estrone (E1), estradiol (E2), and estriol (E3) [1][3] Estradiol, an estrane, is the most potent and prevalent [1] Another estrogen called estetrol (E4) is produced only during pregnancy Estrogens
  • Hydroxylation of estradiol - Wikipedia
    Major routes of metabolism of estradiol, showing hydroxylation The hydroxylation of estradiol is one of the major routes of metabolism of the estrogen steroid hormone estradiol It is hydroxylated into the catechol estrogens 2-hydroxyestradiol and 4-hydroxyestradiol and into estriol (16α-hydroxyestradiol), reactions which are catalyzed by cytochrome P450 enzymes predominantly in the liver, but also in various other tissues
  • Feminizing hormone therapy - Wikipedia
    The most common estrogens used in transgender women include estradiol, which is the predominant natural estrogen in women, and estradiol esters such as estradiol valerate and estradiol cypionate, which are prodrugs of estradiol [2][5][15] Conjugated estrogens (Premarin), which are used in menopausal hormone therapy, and ethinylestradiol, which
  • 17α-Estradiol - Wikipedia
    17α-Estradiol (also known as 17α-E2, 17-epiestradiol, alfatradiol, or estra-1,3,5 (10)-triene-3,17α-diol) is a minor and weak endogenous steroidal estrogen that is related to 17β-estradiol (better known simply as estradiol) [2] It is the C17 epimer of estradiol [2] It has approximately 100-fold lower estrogenic potency than 17β-estradiol [3] The compound shows preferential affinity for the ERα over the ERβ [2][4] Although 17α-estradiol is far weaker than 17β-estradiol as an
  • Phytoestrogen - Wikipedia
    A phytoestrogen is a plant-derived xenoestrogen (a type of estrogen produced by organisms other than humans) not generated within the endocrine system, but consumed by eating plants or manufactured foods [1] Also called a "dietary estrogen", it is a diverse group of naturally occurring nonsteroidal plant compounds that, because of its structural similarity to estradiol (17-β-estradiol), have the ability to cause both estrogenic or antiestrogenic effects [1][2] Phytoestrogens are not





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